Early Chest Imaging in Patients with Puumala Hantavirus Infection

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Pathology of Puumala Hantavirus Infection in Macaques

Hantaviruses are globally important human pathogens that cause hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Capillary leakage is central to hantaviral diseases, but how it develops, has remained unknown. It has been hypothesized that the pathogenesis of hantavirus infection would be a complex interplay between direct viral effects and immunopathological mechanisms. B...

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Cardiopulmonary involvement in Puumala hantavirus infection

BACKGROUND Hantavirus infections cause potentially life-threatening disease in humans world-wide. Infections with American hantaviruses may lead to hantavirus pulmonary syndrome characterised by severe cardiopulmonary distress with high mortality. Pulmonary involvement in European Puumala hantavirus (PUUV) infection has been reported, whereas knowledge of potential cardiac manifestations is lim...

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Polymorphism of the cytokine genes in hospitalized patients with Puumala hantavirus infection.

BACKGROUND Nephropathia epidemica (NE) is a mild type of haemorrhagic fever with renal syndrome caused by Puumala (PUU) hantavirus. The clinical course of NE varies from asymptomatic to fatal. The aim of this study was to establish whether polymorphisms in the cytokine genes are associated with susceptibility to and outcome of NE. METHODS The genotypes of the genes of tumour necrosis factor a...

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Autoimmune polyendocrinopathy and hypophysitis after Puumala hantavirus infection

Puumala hantavirus (PUUV) infection causes nephropathia epidemica (NE), a relatively mild form of haemorrhagic fever with renal syndrome (HFRS). Hypophyseal haemorrhage and hypopituitarism have been described in case reports on patients with acute NE. Chronic hypopituitarism diagnosed months or years after the acute illness has also been reported, without any signs of a haemorrhagic aetiology. ...

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Detection of Puumala Hantavirus Antigen in Human Intestine during Acute Hantavirus Infection

BACKGROUND Puumala virus (PUUV) is the most important hantavirus species in Central Europe. Nephropathia epidemica (NE), caused by PUUV, is characterized by acute renal injury (AKI) with thrombocytopenia and frequently gastrointestinal symptoms. METHODS 456 patients with serologically and clinically confirmed NE were investigated at time of follow-up in a single clinic. The course of the NE w...

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ژورنال

عنوان ژورنال: Journal of the Belgian Society of Radiology

سال: 2020

ISSN: 2514-8281

DOI: 10.5334/jbsr.2039